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Description

Nature 582 , 129133 (2020)

Nutrient replenishment: Reducing food intake or experiencing appetite suppression from GLP-1s may sometimes result in decreased nutrient consumption

1,4 Hyperglycemia, dyslipidemia, and insulin resistance activate various metabolic pathways, resulting in oxidative stress, mitochondrial dysfunction, inflammation, and microvascular damage, culminating in neuronal injury, Schwann cell damage, and myelin sheath degeneration